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KMID : 0360220100510111528
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Journal of the Korean Ophthalmological Society
2010 Volume.51 No. 11 p.1528 ~ p.1531
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Acyclovir-induced Acute Renal Failure in a Patient With Suspected Acute Retinal Necrosis Syndrome
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Cho Joon-Hee
Jang Joo-Hyun
Lee Dong-Hun
Lee Young-Ki
Noh Jung-Woo
Bae Ji-Hyun
Kim Ha-Kyoung
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Abstract
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Purpose:To report a case of acyclovir-induced acute renal failure (ARF) suspected as acute retinal necrosis syndrome.
Case summary: The authors report a 55-year-old male patient who presented with left eye visual disturbance due to suspected acute retinal necrosis syndrome. Non-oliguric ARF developed after the infusion of intravenous acyclovir (850 mg every 8 hours). The patient did not show any uremic symptoms or signs. The crystal was not discovered in the urine. After stopping the acyclovir infusion and hydration, acyclovir-induced ARF was reversed.
Conclusions:Although possessing critical nephrotoxicity, acyclovir is a useful antiviral drug. Therefore, when using acyclovir, the importance of hydration and preventing acyclovir-induced ARF should be considered.
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KEYWORD
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Acute renal failure, Acute retinal necrosis syndrome, Acyclovir
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